Salutary effects of exogenous adenosine administration on in vivo myocardial stunning
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چکیده
منابع مشابه
Effects of endogenous production and exogenous administration of H2S on gastric acid secretion in rats
Introduction: Recently, hydrogen sulfide has been introduced as the third gas that acts as a transmitter. It has many physiological and pharmacological roles in the human body. The aim of the present study was to investigate the effect of exogenously administered and endogenously produced H2S on the basal and distention-induced gastric acid secretion in rats. Methods: Forty-nine male Wistar...
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BACKGROUND Mounting evidence suggests a protective effect of exogenous adenosine in myocardial ischemia and reperfusion. We tested the hypothesis that augmentation of endogenous adenosine levels, achieved by inhibiting adenosine catabolism and washout, is beneficial in postischemic myocardial dysfunction ("stunning"). METHODS AND RESULTS In phase I of the study, open-chest dogs undergoing a 1...
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Myocardial Stunning in Dogs
This study was undertaken to elucidate whether cal-adrenoceptor activity is beneficial to contractile dysfunction during reperfusion after a brief period of ischemia (stunned myocardium) in 54 open-chest dogs. Contractile dysfunction assessed by fractional shortening (FS) was observed 3 hours after the onset of reperfusion following 15 minutes of complete occlusion of the left anterior descendi...
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ژورنال
عنوان ژورنال: The Journal of Thoracic and Cardiovascular Surgery
سال: 1995
ISSN: 0022-5223
DOI: 10.1016/s0022-5223(05)80010-8